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dc.contributor.authorAllgar, Ven
dc.contributor.authorWright, Ben
dc.contributor.authorTaylor, Aen
dc.contributor.authorCouter, ALen
dc.contributor.authorPhillips, Hen
dc.date.accessioned2021-10-25T11:16:16Z
dc.date.issued2021-09-24en
dc.identifier.issn2077-0383en
dc.identifier.urihttp://hdl.handle.net/10026.1/18169
dc.description.abstract

<jats:p>The aim was to investigate the agreement between the ADI-R Deaf adaptation and ADOS-2 Deaf adaptation overall diagnostic categorisation for autism (AUT) and a wider threshold to include autism spectrum (ASD) in a cohort of deaf children with and without ASD. We compared results of the instruments used on their own and when combined and propose standard criteria for the combined use of the ADI-R Deaf adaptation and ADOS-2 Deaf adaptation for use with deaf children. In total, 116 deaf children had a Gold standard NICE guideline assessment; 58 diagnosed with ASD and 58 without ASD, and for both groups a blinded informant based ADI-R Deaf adaptation and direct assessment using the ADOS-2 Deaf adaptation were separately completed. There was moderate agreement between the ADI-R Deaf adaptation and ADOS-2 Deaf adaptation for the wider threshold of ASD (Kappa, 0.433). To achieve the lowest number of false negatives, the most successful assessment tool approach is using the wider threshold of ASD with either ADI-R Deaf adaptation or ADOS-2-Deaf adaptation (95% sensitivity). This compares with 88% for the ADI-R Deaf adaptation alone and 74% for the ADOS-2-Deaf adaptation alone (wider threshold of ASD). To achieve a low number of false positives, the most successful assessment tool approach is a combination of ADI-R Deaf adaptation and ADOS-2- Deaf adaptation (using the narrow threshold of autism for both) (95% specificity). This compares with 83% for the ADI-R Deaf adaptation alone and 81% for the ADOS-2-Deaf adaptation (narrow threshold) alone. This combination is therefore recommended in specialist clinics for diagnostic assessment in deaf children.</jats:p>

en
dc.format.extent4374 - 4374en
dc.languageenen
dc.language.isoenen
dc.publisherMDPIen
dc.titleDiagnosing Autism Spectrum Disorders in Deaf Children Using Two Standardised Assessment Instruments: The ADIR-Deaf Adaptation and the ADOS-2 Deaf Adaptationen
dc.typeJournal Article
plymouth.issue19en
plymouth.volume10en
plymouth.journalJournal of Clinical Medicineen
dc.identifier.doi10.3390/jcm10194374en
plymouth.organisational-group/Plymouth
plymouth.organisational-group/Plymouth/Faculty of Health
plymouth.organisational-group/Plymouth/Faculty of Health/Peninsula Medical School
plymouth.organisational-group/Plymouth/REF 2021 Researchers by UoA
plymouth.organisational-group/Plymouth/REF 2021 Researchers by UoA/UoA01 Clinical Medicine
plymouth.organisational-group/Plymouth/Users by role
plymouth.organisational-group/Plymouth/Users by role/Academics
dcterms.dateAccepted2021-09-20en
dc.rights.embargodate2021-10-26en
dc.identifier.eissn2077-0383en
dc.rights.embargoperiodNot knownen
rioxxterms.versionofrecord10.3390/jcm10194374en
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserveden
rioxxterms.licenseref.startdate2021-09-24en
rioxxterms.typeJournal Article/Reviewen


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