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dc.contributor.authorLalabekyan, BB
dc.contributor.authorTetlow, N
dc.contributor.authorMoonesinghe, R
dc.contributor.authorMartin, D
dc.contributor.authorBurdett, E
dc.contributor.authorOtto, J
dc.contributor.authorWyndham, D
dc.contributor.authorBettini, E
dc.contributor.authorKalavrezos, N
dc.contributor.authorStephens, RCM
dc.date.accessioned2020-09-18T10:37:22Z
dc.date.available2020-09-18T10:37:22Z
dc.date.issued2021-04
dc.identifier.issn0266-4356
dc.identifier.issn1532-1940
dc.identifier.urihttp://hdl.handle.net/10026.1/16385
dc.description.abstract

Cardiopulmonary exercise testing (CPET) is used as a risk stratification tool for patients undergoing major surgery. In this study, we investigated the role of CPET in predicting day five cardiopulmonary morbidity in patients undergoing head and neck surgery. This observational cohort study included 230 adults. We recorded preoperative CPET variables and day five postoperative cardiopulmonary morbidity. Full data from 187 patients were analysed; 43 patients either had incomplete data sets or declined surgery/CPET. One hundred and nineteen patients (63.6%) developed cardiopulmonary morbidity at day five. Increased preoperative heart rate and duration of surgery were independently associated with day five cardiopulmonary morbidity. Those with such morbidity also had lower peak V̇O2 11.4 (IQR 8.4-18.0) vs 16.0 (IQR 14.0-19.7) ml.kg-1.min-1, P<0.0001 and V̇O2 at AT 10.6 (IQR 9.1-13.1) vs 11.5 (IQR 10.5-13.0) ml.kg-1.min-1, p=0.03. Logistic regression model containing peak V̇O2 and duration of surgery demonstrated that increased peak V̇O2 was associated with a reduction in the likelihood of cardiopulmonary complications OR 0.92 (95%CI 0.87 to 0.96), p=0.001. The area under the receiver operating characteristic curve for this model was 0.75(95%CI 0.68 to 0.82), p<0.0001, 64% sensitivity, 81% specificity. CPET can help to predict day five cardiopulmonary morbidity in the patients undergoing head and neck surgery. A model containing peak V̇O2 allowed identification of those with such complications.

dc.format.extent297-302
dc.format.mediumPrint-Electronic
dc.languageen
dc.language.isoen
dc.publisherElsevier BV
dc.subjectCardiopulmonary exercise testing
dc.subjectpostoperative morbidity
dc.subjectmaxillofacial surgery
dc.subjectrisk stratification
dc.titleCardiopulmonary exercise testing and cardiopulmonary morbidity in patients undergoing major head and neck surgery
dc.typejournal-article
dc.typeArticle
plymouth.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/33589309
plymouth.issue3
plymouth.volume59
plymouth.publisher-urlhttp://dx.doi.org/10.1016/j.bjoms.2020.08.032
plymouth.publication-statusPublished
plymouth.journalBritish Journal of Oral and Maxillofacial Surgery
dc.identifier.doi10.1016/j.bjoms.2020.08.032
plymouth.organisational-group/Plymouth
plymouth.organisational-group/Plymouth/Faculty of Health
plymouth.organisational-group/Plymouth/REF 2021 Researchers by UoA
plymouth.organisational-group/Plymouth/REF 2021 Researchers by UoA/UoA01 Clinical Medicine
plymouth.organisational-group/Plymouth/Users by role
plymouth.organisational-group/Plymouth/Users by role/Academics
dc.publisher.placeScotland
dcterms.dateAccepted2020-08-10
dc.rights.embargodate2022-2-13
dc.identifier.eissn1532-1940
dc.rights.embargoperiodNot known
rioxxterms.versionofrecord10.1016/j.bjoms.2020.08.032
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.licenseref.startdate2021-04
rioxxterms.typeJournal Article/Review


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