Show simple item record

dc.contributor.authorChiaravalloti, ND
dc.contributor.authorAmato, MP
dc.contributor.authorBrichetto, G
dc.contributor.authorChataway, J
dc.contributor.authorDalgas, U
dc.contributor.authorDeLuca, J
dc.contributor.authorMeza, C
dc.contributor.authorMoore, NB
dc.contributor.authorFeys, P
dc.contributor.authorFilippi, M
dc.contributor.authorFreeman, Jennifer
dc.contributor.authorInglese, M
dc.contributor.authorMotl, R
dc.contributor.authorRocca, MA
dc.contributor.authorSandroff, BM
dc.contributor.authorSalter, A
dc.contributor.authorCutter, G
dc.contributor.authorFeinstein, A
dc.date.accessioned2020-09-15T07:29:16Z
dc.date.issued2020-08-19
dc.identifier.issn0340-5354
dc.identifier.issn1432-1459
dc.identifier.urihttp://hdl.handle.net/10026.1/16258
dc.descriptionEmbargo removed due to subject matter.
dc.description.abstract

OBJECTIVE: Individuals with pre-existing chronic illness have shown increased anxiety and depression due to COVID-19. Here, we examine the impact of the COVID-19 pandemic on emotional symptomatology and quality of life in individuals with Progressive Multiple Sclerosis (PMS). METHODS: Data were obtained during a randomized clinical trial on rehabilitation taking place at 11 centers in North America and Europe. Participants included 131 individuals with PMS. Study procedures were interrupted in accordance with governmental restrictions as COVID-19 spread. During study closure, a COVID Impact Survey was administered via telephone or email to all participants, along with measures of depressive symptoms, anxiety symptoms, quality of life, and MS symptomatology that were previously administered pre-pandemic. RESULTS: 4% of respondents reported COVID-19 infection. No significant changes were noted in anxiety, quality of life, or the impact of MS symptomatology on daily life from baseline to lockdown. While total HADS-depression scores increased significantly at follow-up, this did not translate into more participants scoring above the HADS threshold for clinically significant depression. No significant relationships were noted between disease duration, processing speed ability or EDSS, and changes in symptoms of depression or anxiety. Most participants reported the impact of the virus on their psychological well-being, with a little impact on financial well-being. The perceived impact of the pandemic on physical and psychological well-being was correlated with the impact of MS symptomatology on daily life, as well as changes in depression. CONCLUSIONS: Overall, little change was noted in symptoms of depression or anxiety or overall quality of life.

dc.format.extent1598-1607
dc.format.mediumPrint-Electronic
dc.languageen
dc.language.isoen
dc.publisherSpringer Science and Business Media LLC
dc.subjectCOVID-19
dc.subjectDepression
dc.subjectAnxiety
dc.subjectProgressive multiple sclerosis
dc.subjectQuality of life
dc.titleThe emotional impact of the COVID-19 pandemic on individuals with progressive multiple sclerosis
dc.typejournal-article
dc.typeJournal Article
dc.typeRandomized Controlled Trial
plymouth.author-urlhttps://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000561058200003&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=11bb513d99f797142bcfeffcc58ea008
plymouth.issue5
plymouth.volume268
plymouth.publication-statusPublished
plymouth.journalJournal of Neurology
dc.identifier.doi10.1007/s00415-020-10160-7
plymouth.organisational-group/Plymouth
plymouth.organisational-group/Plymouth/Faculty of Health
plymouth.organisational-group/Plymouth/Faculty of Health/School of Health Professions
plymouth.organisational-group/Plymouth/REF 2021 Researchers by UoA
plymouth.organisational-group/Plymouth/REF 2021 Researchers by UoA/UoA03 Allied Health Professions, Dentistry, Nursing and Pharmacy
plymouth.organisational-group/Plymouth/Research Groups
plymouth.organisational-group/Plymouth/Research Groups/Institute of Health and Community
plymouth.organisational-group/Plymouth/Research Groups/Plymouth Institute of Health and Care Research (PIHR)
plymouth.organisational-group/Plymouth/Users by role
plymouth.organisational-group/Plymouth/Users by role/Academics
plymouth.organisational-group/Plymouth/Users by role/Researchers in ResearchFish submission
dc.publisher.placeGermany
dcterms.dateAccepted2020-08-11
dc.rights.embargodate2020-10-2
dc.identifier.eissn1432-1459
dc.rights.embargoperiodNot known
rioxxterms.versionofrecord10.1007/s00415-020-10160-7
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.licenseref.startdate2020-08-19
rioxxterms.typeJournal Article/Review


Files in this item

Thumbnail
Thumbnail

This item appears in the following Collection(s)

Show simple item record


All items in PEARL are protected by copyright law.
Author manuscripts deposited to comply with open access mandates are made available in accordance with publisher policies. Please cite only the published version using the details provided on the item record or document. In the absence of an open licence (e.g. Creative Commons), permissions for further reuse of content should be sought from the publisher or author.
Theme by 
Atmire NV