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dc.contributor.authorvon der Lühe, Ben
dc.contributor.authorMayes, RWen
dc.contributor.authorThiel, Ven
dc.contributor.authorDawson, LAen
dc.contributor.authorGraw, Men
dc.contributor.authorRowland, SJen
dc.contributor.authorFiedler, Sen
dc.date.accessioned2020-08-25T14:39:11Z
dc.date.issued2019-12-04en
dc.identifier.urihttp://hdl.handle.net/10026.1/16191
dc.description.abstract

To date, the only known occurrence of ambrein, an important perfumery organic molecule, is in coproliths found in about one in a hundred sperm whales. Jetsam ambergris coproliths from the whale are also found occasionally on beaches worldwide. Here we report on the surprising occurrence of ambrein in human adipocere. Adipocere is a waxy substance formed post-mortem during incomplete anaerobic decomposition of soft tissues. Adipocere samples obtained from grave exhumations were analysed using gas chromatography-mass spectrometry (GC-MS). In addition to the typical fatty acids of adipocere, lesser amounts of ambrein were identified in the samples, in abundances similar to those of the major accompanying faecal steroids. The distribution of these compounds suggests that ambrein was produced post-mortem during the microbial decomposition of faecal residues and tissues. It is assumed that the adipocere matrix of saturated fatty acidsaided the preservation of ambrein over extended periods of time, because adipocere is stable against degradation. The association of ambrein formation in ageing faecal material, under moist, oxygen-depleted conditions, now requires more attention in studies of other mammalian and geological samples. Indeed, ambrein and its transformation products may be useful novel chemical indicators of aged faecal matter and decomposed bodies.

en
dc.format.extent18370 - ?en
dc.languageengen
dc.language.isoengen
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internationalen
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/en
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/en
dc.subjectAdipose Tissueen
dc.subjectAnimalsen
dc.subjectBurialen
dc.subjectExhumationen
dc.subjectFatty Acidsen
dc.subjectGas Chromatography-Mass Spectrometryen
dc.subjectHumansen
dc.subjectNaphtholsen
dc.subjectPostmortem Changesen
dc.subjectSperm Whaleen
dc.subjectTriterpenesen
dc.titleFirst evidence of terrestrial ambrein formation in human adipocere.en
dc.typeJournal Article
plymouth.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/31797886en
plymouth.issue1en
plymouth.volume9en
plymouth.publication-statusPublished onlineen
plymouth.journalSci Repen
dc.identifier.doi10.1038/s41598-019-54730-wen
plymouth.organisational-group/Plymouth
plymouth.organisational-group/Plymouth/Faculty of Science and Engineering
plymouth.organisational-group/Plymouth/Research Groups
plymouth.organisational-group/Plymouth/Research Groups/Marine Institute
plymouth.organisational-group/Plymouth/Users by role
plymouth.organisational-group/Plymouth/Users by role/Professional Services staff
dc.publisher.placeEnglanden
dcterms.dateAccepted2019-11-19en
dc.rights.embargodate9999-12-31en
dc.identifier.eissn2045-2322en
dc.rights.embargoperiodNot knownen
rioxxterms.versionofrecord10.1038/s41598-019-54730-wen
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/en
rioxxterms.licenseref.startdate2019-12-04en
rioxxterms.typeJournal Article/Reviewen


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