Show simple item record

dc.contributor.authorFernández-Méndez, Ren
dc.contributor.authorRichards, HKen
dc.contributor.authorSeeley, HMen
dc.contributor.authorPickard, JDen
dc.contributor.authorJoannides, AJen
dc.contributor.authorUKSR collaboratorsen
dc.date.accessioned2019-11-25T21:48:24Z
dc.date.issued2019-07en
dc.identifier.urihttp://hdl.handle.net/10026.1/15186
dc.description.abstract

OBJECTIVES: To determine current epidemiology and clinical characteristics of cerebrospinal fluid (CSF) shunt surgery, including revisions. METHODS: A retrospective, multicentre, registry-based study was conducted based on 10 years' data from the UK Shunt Registry, including primary and revision shunting procedures reported between 2004 and 2013. Incidence rates of primary shunts, descriptive statistics and shunt revision rates were calculated stratified by age group, geographical region and year of operation. RESULTS: 41 036 procedures in 26 545 patients were submitted during the study period, including 3002 infants, 4389 children and 18 668 adults. Procedures included 20 947 (51.0%) primary shunt insertions in 20 947 patients, and 20 089 (49.0%) revision procedures. Incidence rates of primary shunt insertions for infants, children and adults were 39.5, 2.4 and 3.5 shunts per 100 000 person-years, respectively. These varied by geographical subregion and year of operation. The most common underlying diagnoses were perinatal intraventricular haemorrhage (35.3%) and malformations (33.9%) in infants, tumours (40.5%) and malformations (16.3%) in children, and tumours (24.6%), post-haemorrhagic hydrocephalus (16.2%) and idiopathic normal pressure hydrocephalus (14.2%) in adults. Ninety-day revision rates were 21.9%, 18.6% and 12.8% among infants, children and adults, respectively, while first-year revision rates were 31.0%, 25.2% and 17.4%. The main reasons for revision were underdrainage and infection, but overdrainage and mechanical failure continue to pose problems. CONCLUSIONS: Our report informs patients, carers, clinicians, providers and commissioners of healthcare, researchers and industry of the current epidemiology of shunting for CSF disorders, including the potential risks of complications and frequency of revision.

en
dc.format.extent747 - 754en
dc.languageengen
dc.language.isoengen
dc.subjectCSF shuntingen
dc.subjectEpidemiologyen
dc.subjectNeurosurgeryen
dc.subjectRegistryen
dc.subjectAdolescenten
dc.subjectAdulten
dc.subjectAge Factorsen
dc.subjectAgeden
dc.subjectCerebrospinal Fluid Shuntsen
dc.subjectChilden
dc.subjectChild, Preschoolen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectInfanten
dc.subjectInfant, Newbornen
dc.subjectIrelanden
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectRegistriesen
dc.subjectReoperationen
dc.subjectRetrospective Studiesen
dc.subjectSex Factorsen
dc.subjectUnited Kingdomen
dc.subjectYoung Adulten
dc.titleCurrent epidemiology of cerebrospinal fluid shunt surgery in the UK and Ireland (2004-2013).en
dc.typeJournal Article
plymouth.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/30910858en
plymouth.issue7en
plymouth.volume90en
plymouth.publication-statusPublisheden
plymouth.journalJ Neurol Neurosurg Psychiatryen
dc.identifier.doi10.1136/jnnp-2018-319927en
plymouth.organisational-group/Plymouth
plymouth.organisational-group/Plymouth/00 Groups by role
plymouth.organisational-group/Plymouth/00 Groups by role/Professional Services staff
plymouth.organisational-group/Plymouth/Faculty of Health: Medicine, Dentistry and Human Sciences
plymouth.organisational-group/Plymouth/Faculty of Health: Medicine, Dentistry and Human Sciences/Peninsula Medical School
dc.publisher.placeEnglanden
dcterms.dateAccepted2019-02-10en
dc.rights.embargodate9999-12-31en
dc.identifier.eissn1468-330Xen
dc.rights.embargoperiodNot knownen
rioxxterms.versionofrecord10.1136/jnnp-2018-319927en
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserveden
rioxxterms.licenseref.startdate2019-07en
rioxxterms.typeJournal Article/Reviewen


Files in this item

Thumbnail
Thumbnail

This item appears in the following Collection(s)

Show simple item record


All items in PEARL are protected by copyright law.
Author manuscripts deposited to comply with open access mandates are made available in accordance with publisher policies. Please cite only the published version using the details provided on the item record or document. In the absence of an open licence (e.g. Creative Commons), permissions for further reuse of content should be sought from the publisher or author.
Theme by 
@mire NV