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dc.contributor.authorHickson, Mary
dc.contributor.authorLamarti, E
dc.date.accessioned2019-11-06T15:03:08Z
dc.date.issued2020-06
dc.identifier.issn0952-3871
dc.identifier.issn1365-277X
dc.identifier.urihttp://hdl.handle.net/10026.1/15123
dc.description.abstract

<jats:title>Abstract</jats:title><jats:sec><jats:title>Background</jats:title><jats:p>There is a high prevalence of malnutrition among people with decompensated liver disease. Standard nutritional screening tools use weight and body mass index (BMI) to identify risk, although these are difficult to measure for those with ascites, often secondary to liver cirrhosis. Dietetic guidance suggests adjusting for ascitic weight by 2.2–14 kg, although there is a lack of evidence to substantiate these values. The present study aimed to measure the contribution of ascitic fluid weight and compare this with the current guidance, as well as to examine whether girth circumference can be used to estimate ascitic weight.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>A cross‐sectional, observational study was conducted over 13 weeks. Participants attending for paracentesis were weighed, their girths measured, and BMI was calculated pre‐ and post‐paracentesis. Fluid removed via paracentesis was recorded. Ethical approval was received (IRAS project ID: 218747).</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Eighteen participants underwent paracentesis. The range of ascitic fluid drained was 3.8–19 L [mean (SD) = 8.7 (3.7) L]. Weight difference between pre‐ and post‐paracentesis was in the range 4.5–20 kg [mean (SD) = 8.7 (3.9) kg]. Ascitic fluid weight is shown to be higher in each category (minimal, moderate, severe ascites) than the current guidance values. Weight difference was greater than 14 kg in 11% (<jats:italic>n</jats:italic> = 2) of participants. A strong, statistically significant relationship (rho = 0.68, <jats:italic>P</jats:italic> ≤ 0.01) between ascitic weight and pre‐paracentesis girth was found. An equation was formulated to enable the estimation of ascitic fluid from pre‐paracentesis girth.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>Current dietetic guidance should be re‐evaluated to reflect the greater weight differences identified. Measuring girth pre‐paracentesis may help to inform dry weight estimation. Further research is required to verify the accuracy of estimating ascitic weight from pre‐paracentesis girth.</jats:p></jats:sec>

dc.format.extent404-413
dc.format.mediumPrint-Electronic
dc.languageen
dc.language.isoen
dc.publisherWiley
dc.subjectalcoholic liver disease
dc.subjectascites
dc.subjectbody mass index
dc.subjectcirrhosis
dc.subjectgirth
dc.subjectliver
dc.subjectweight
dc.titleThe contribution of ascitic fluid to body weight in patients with liver cirrhosis, and its estimation using girth: a cross-sectional observational study
dc.typejournal-article
dc.typeJournal Article
dc.typeObservational Study
dc.typeResearch Support, Non-U.S. Gov't
plymouth.author-urlhttps://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000498774200001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=11bb513d99f797142bcfeffcc58ea008
plymouth.issue3
plymouth.volume33
plymouth.publication-statusPublished
plymouth.journalJournal of Human Nutrition and Dietetics
dc.identifier.doi10.1111/jhn.12721
plymouth.organisational-group/Plymouth
plymouth.organisational-group/Plymouth/Faculty of Health
plymouth.organisational-group/Plymouth/Faculty of Health/School of Health Professions
plymouth.organisational-group/Plymouth/REF 2021 Researchers by UoA
plymouth.organisational-group/Plymouth/REF 2021 Researchers by UoA/UoA03 Allied Health Professions, Dentistry, Nursing and Pharmacy
plymouth.organisational-group/Plymouth/Research Groups
plymouth.organisational-group/Plymouth/Research Groups/Institute of Health and Community
plymouth.organisational-group/Plymouth/Research Groups/Plymouth Institute of Health and Care Research (PIHR)
plymouth.organisational-group/Plymouth/Users by role
plymouth.organisational-group/Plymouth/Users by role/Academics
dc.publisher.placeEngland
dcterms.dateAccepted2019-11-04
dc.rights.embargodate2020-11-26
dc.identifier.eissn1365-277X
dc.rights.embargoperiodNot known
rioxxterms.versionofrecord10.1111/jhn.12721
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.typeJournal Article/Review


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