Browsing School of Biomedical Sciences by Title
Now showing items 233-252 of 270
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Self-disseminating vaccines for emerging infectious diseases.
(England, 2016)Modern human activity fueled by economic development is profoundly altering our relationship with microorganisms. This altered interaction with microbes is believed to be the major driving force behind the increased rate ... -
The Serum Resistome of a Globally Disseminated Multidrug Resistant Uropathogenic <italic>Escherichia coli</italic> Clone
(Public Library of Science, 2013-10-03)<title>Author Summary</title> The emergence and rapid dissemination of new bacterial pathogens presents multiple challenges to healthcare systems, including the need for rapid detection, precise diagnostics, effective ... -
Short RNA half-lives in the slow-growing marine cyanobacterium Prochlorococcus.
(England, 2010)BACKGROUND: RNA turnover plays an important role in the gene regulation of microorganisms and influences their speed of acclimation to environmental changes. We investigated whole-genome RNA stability of Prochlorococcus, ... -
StemCellNet: an interactive platform for network-oriented investigations in stem cell biology.
(England, 2014-07)Stem cells are characterized by their potential for self-renewal and their capacity to differentiate into mature cells. These two key features emerge through the interplay of various factors within complex molecular ... -
StemChecker: a web-based tool to discover and explore stemness signatures in gene sets.
(England, 2015-07-01)Stem cells present unique regenerative abilities, offering great potential for treatment of prevalent pathologies such as diabetes, neurodegenerative and heart diseases. Various research groups dedicated significant effort ... -
StemMapper: a curated gene expression database for stem cell lineage analysis.
(England, 2018-01-04)Transcriptomic data have become a fundamental resource for stem cell (SC) biologists as well as for a wider research audience studying SC-related processes such as aging, embryonic development and prevalent diseases ... -
Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis
(Springer Science and Business Media LLC, 2019-12) -
Systematic Analysis and Biomarker Study for Alzheimer's Disease
(Nature Research (part of Springer Nature), 2018-11-26) -
Tailoring 3D single-walled carbon nanotubes anchored to indium tin oxide for natural cellular uptake and intracellular sensing.
(United States, 2013-01-09)The ability to monitor intracellular events in real time is paramount to advancing fundamental biological and clinical science. We present the first demonstration of a direct interface of vertically aligned single-walled ... -
Targeting molecular networks for drug research.
(Switzerland, 2014)The study of molecular networks has recently moved into the limelight of biomedical research. While it has certainly provided us with plenty of new insights into cellular mechanisms, the challenge now is how to modify or ... -
TetAB46, a predicted heterodimeric ABC transporter conferring tetracycline resistance in Streptococcus australis isolated from the oral cavity.
(England, 2013-01)OBJECTIVES: To identify the genes responsible for tetracycline resistance in a strain of Streptococcus australis isolated from pooled saliva from healthy volunteers in France. S. australis is a viridans Streptococcus, ... -
Toll-like receptor and IL-12 signaling control susceptibility to contact hypersensitivity.
(United States, 2008-09-01)Allergic contact hypersensitivity (CHS) is a T cell-mediated inflammatory skin disease. Interleukin (IL)-12 is considered to be important in the generation of the allergen-specific T cell response. Loss of IL-12 function ... -
Toward a systems-level understanding of gene regulatory, protein interaction, and metabolic networks in cyanobacteria.
(Switzerland, 2014)Cyanobacteria are essential primary producers in marine ecosystems, playing an important role in both carbon and nitrogen cycles. In the last decade, various genome sequencing and metagenomic projects have generated large ... -
The Transcriptional Landscape of the Photosynthetic Model Cyanobacterium Synechocystis sp. PCC6803.
(England, 2016-02-29)Cyanobacteria exhibit a great capacity to adapt to different environmental conditions through changes in gene expression. Although this plasticity has been extensively studied in the model cyanobacterium Synechocystis sp. ...