Show simple item record

dc.contributor.authorRoberts, A
dc.contributor.authorBorisyuk, Roman
dc.contributor.authorBuhl, E
dc.contributor.authorFerrario, A
dc.contributor.authorKoutsikou, S
dc.contributor.authorLi, W-C
dc.contributor.authorSoffe, SR
dc.date.accessioned2019-05-13T09:58:52Z
dc.date.available2019-05-13T09:58:52Z
dc.date.issued2019-03
dc.identifier.issn0962-8452
dc.identifier.issn1471-2954
dc.identifier.otherARTN 20190297
dc.identifier.urihttp://hdl.handle.net/10026.1/13851
dc.description.abstract

All animals use sensory systems to monitor external events and have to decide whether to move. Response times are long and variable compared to reflexes, and fast escape movements. The complexity of adult vertebrate brains makes it difficult to trace the neuronal circuits underlying basic decisions to move. To simplify the problem, we investigate the nervous system and responses of hatchling frog tadpoles which swim when their skin is stimulated. Studying the neuron-by-neuron pathway from sensory to hindbrain neurons, where the decision to swim is made, has revealed two simple pathways generating excitation which sums to threshold in these neurons to initiate swimming. The direct pathway leads to short, and reliable delays like an escape response. The other includes a population of sensory processing neurons which extend firing to introduce noise and delay into responses. These neurons provide a brief, sensory memory of the stimulus, that allows tadpoles to integrate stimuli occurring within a second or so of each other. We relate these findings to other studies and conclude that sensory memory makes a fundamental contribution to simple decisions and is present in the brainstem of a basic vertebrate at a surprisingly early stage in development.

dc.format.extent20190297-20190297
dc.format.mediumPrint
dc.languageen
dc.language.isoen
dc.publisherRoyal Society, The
dc.subjectdecisions
dc.subjectlocomotion
dc.subjectresponse times
dc.subjectsensory memory
dc.titleThe decision to move: response times, neuronal circuits and sensory memory in a simple vertebrate
dc.typejournal-article
dc.typeJournal Article
dc.typeResearch Support, Non-U.S. Gov't
dc.typeReview
plymouth.author-urlhttps://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000465434800019&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=11bb513d99f797142bcfeffcc58ea008
plymouth.issue1899
plymouth.volume286
plymouth.publication-statusPublished
plymouth.journalProceedings of the Royal Society B: Biological Sciences
dc.identifier.doi10.1098/rspb.2019.0297
plymouth.organisational-group/Plymouth
plymouth.organisational-group/Plymouth/Faculty of Science and Engineering
plymouth.organisational-group/Plymouth/Users by role
plymouth.organisational-group/Plymouth/Users by role/Researchers in ResearchFish submission
dc.publisher.placeEngland
dcterms.dateAccepted2019-02-28
dc.rights.embargodate9999-12-31
dc.identifier.eissn1471-2954
dc.rights.embargoperiodNot known
rioxxterms.versionofrecord10.1098/rspb.2019.0297
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.licenseref.startdate2019-03
rioxxterms.typeJournal Article/Review
plymouth.funderCross-modality integration of sensory signals leading to initiation of locomotion::BBSRC
plymouth.funderCross-modality integration of sensory signals leading to initiation of locomotion::BBSRC


Files in this item

Thumbnail
Thumbnail

This item appears in the following Collection(s)

Show simple item record


All items in PEARL are protected by copyright law.
Author manuscripts deposited to comply with open access mandates are made available in accordance with publisher policies. Please cite only the published version using the details provided on the item record or document. In the absence of an open licence (e.g. Creative Commons), permissions for further reuse of content should be sought from the publisher or author.
Theme by 
Atmire NV