Browsing School of Biological and Marine Sciences by Subject "Autophagy"
Now showing items 1-1 of 1
Long Term Aggresome Accumulation Leads to DNA Damage, p53-dependent Cell Cycle Arrest, and Steric Interference in Mitosis. (United States, 2015-11-13)Juxtanuclear aggresomes form in cells when levels of aggregation-prone proteins exceed the capacity of the proteasome to degrade them. It is widely believed that aggresomes have a protective function, sequestering potentially ...