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Huntington's disease and its therapeutic target genes: a global functional profile based on the HD Research Crossroads database.
BACKGROUND: Huntington's disease (HD) is a fatal progressive neurodegenerative disorder caused by the expansion of the polyglutamine repeat region in the huntingtin gene. Although the disease is triggered by the mutation ...
UniHI: an entry gate to the human protein interactome.
Systematic mapping of protein-protein interactions has become a central task of functional genomics. To map the human interactome, several strategies have recently been pursued. The generated interaction datasets are ...
UniHI 4: new tools for query, analysis and visualization of the human protein-protein interactome.
Human protein interaction maps have become important tools of biomedical research for the elucidation of molecular mechanisms and the identification of new modulators of disease processes. The Unified Human Interactome ...
UniHI 7: an enhanced database for retrieval and interactive analysis of human molecular interaction networks.
Unified Human Interactome (UniHI) (http://www.unihi.org) is a database for retrieval, analysis and visualization of human molecular interaction networks. Its primary aim is to provide a comprehensive and easy-to-use platform ...