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Heat-killed probiotic bacteria differentially regulate colonic epithelial cell production of human β-defensin-2: dependence on inflammatory cytokines.
The inducible antimicrobial peptide human β-defensin-2 (hBD-2) stimulated by pro-inflammatory cytokines and bacterial products is essential to antipathogen responses of gut epithelial cells. Commensal and probiotic bacteria ...
Lactobacillus casei strain Shirota selectively modulates macrophage subset cytokine production
Probiotics confer health benefits through many mechanisms including modulation of the gut immune system, dut macrophages regulate immune homeostasis, mounting tolerogenic responses to food and commensal bacteria or immune ...
Probiotic bacterial strains differentially modulate macrophage cytokine production in a strain-dependent and cell subset-specific manner.
Gut mucosal macrophages play a pivotal role in driving mucosal immune responses, resulting in either activation of inflammatory immune responses to pathogenic challenge or tolerance to beneficial luminal contents such as ...