Now showing items 21-30 of 163
Gender-questioning children deserve better science.
Towards an alternative testing strategy for nanomaterials used in nanomedicine: lessons from NanoTEST.
In spite of recent advances in describing the health outcomes of exposure to nanoparticles (NPs), it still remains unclear how exactly NPs interact with their cellular targets. Size, surface, mass, geometry, and composition ...
Uptake of different crystal structures of TiO₂ nanoparticles by Caco-2 intestinal cells.
The gastrointestinal uptake of different crystal structures of TiO2 was investigated using Caco-2 intestinal cells. Caco-2 monolayers exhibited time-dependent, saturable uptake of Ti from TiO2 exposures of 1 mgl(-1) over ...
Biological impact assessment of nanomaterial used in nanomedicine. introduction to the NanoTEST project.
Therapeutic nanoparticles (NPs) are used in nanomedicine as drug carriers or imaging agents, providing increased selectivity/specificity for diseased tissues. The first NPs in nanomedicine were developed for increasing the ...
Achieving valid patient-reported outcomes measurement: a lesson from fatigue in multiple sclerosis.
BACKGROUND: The increasing influence of patient-reported outcome (PRO) measurement instruments indicates their scrutiny has never been more crucial. Above all, PRO instruments should be valid: shown to assess what they ...
Measuring treatment satisfaction in MS: Is the Treatment Satisfaction Questionnaire for Medication fit for purpose?
BACKGROUND: The Treatment Satisfaction Questionnaire for Medication (TSQM) was designed to assess patient treatment satisfaction in chronic diseases. Its performance has not been examined in multiple sclerosis (MS). The ...
Gastrostomy in patients with amyotrophic lateral sclerosis (ProGas): a prospective cohort study.
BACKGROUND: Gastrostomy feeding is commonly used to support patients with amyotrophic lateral sclerosis who develop severe dysphagia. Although recommended by both the American Academy of Neurology and the European Federation ...
Neurofibromatosis 2011: a report of the Children's Tumor Foundation annual meeting.
The 2011 annual meeting of the Children's Tumor Foundation, the annual gathering of the neurofibromatosis (NF) research and clinical communities, was attended by 330 participants who discussed integration of new signaling ...
Referrals to a regional allergy clinic - an eleven year audit.
BACKGROUND: Allergy is a serious and apparently increasing public health problem yet relatively little is known about the types of allergy seen in routine tertiary practice, including their spatial distribution, co-occurrence ...