Now showing items 1-10 of 27
The role of insulin-like growth factors signaling in merlin-deficient human schwannomas.
Loss of the tumor suppressor merlin causes development of the tumors of the nervous system, such as schwannomas, meningiomas, and ependymomas occurring spontaneously or as part of a hereditary disease Neurofibromatosis ...
Changes in iron-regulatory gene expression occur in human cell culture models of Parkinson's disease.
BACKGROUND: Neuronal iron accumulation is thought to be relevant to the pathogenesis of Parkinson's disease (PD), although the mechanism remains elusive. We hypothesized that neuronal iron uptake may be stimulated by ...
An essential role for the tumor suppressor Merlin in regulating fatty acid synthesis.
Neurofibromatosis type 2 (NF2) is an autosomal dominant disorder characterized by the development of multiple tumors in the central nervous system, most notably schwannomas and meningiomas. Mutational inactivation of the ...
Neurofibromatosis 2011: a report of the Children's Tumor Foundation annual meeting.
The 2011 annual meeting of the Children's Tumor Foundation, the annual gathering of the neurofibromatosis (NF) research and clinical communities, was attended by 330 participants who discussed integration of new signaling ...