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  • Roles of tetrahydrobiopterin in promoting tumor angiogenesis. 

    Chen, L; Zeng, X; Wang, J; Briggs, SS; O'Neill, E; Li, J; Leek, R; Kerr, DJ; Harris, AL; Cai, S (United States, 2010-11)
    Nitric oxide (NO), which is derived from endothelial NO synthase (eNOS), provides crucial signals for angiogenesis in the tumor microenvironment. Tetrahydrobiopterin (BH4) is an absolute requirement for eNOS activity. In ...

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