Browsing University of Plymouth Research Outputs by Subject "ADAM Proteins"
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ADAM10 mediates trastuzumab resistance and is correlated with survival in HER2 positive breast cancer. (United States, 2014-08-30)Trastuzumab prolongs survival in HER2 positive breast cancer patients. However, resistance remains a challenge. We have previously shown that ADAM17 plays a key role in maintaining HER2 phosphorylation during trastuzumab ...