Browsing University of Plymouth Research Outputs by Title
Now showing items 1312-1331 of 1630
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Safety and efficacy of diaphragm pacing in patients with respiratory insufficiency due to amyotrophic lateral sclerosis (DiPALS): a multicentre, open-label, randomised controlled trial.
(England, 2015-09)BACKGROUND: Non-invasive ventilation is part of the standard of care for treatment of respiratory failure in patients with amyotrophic lateral sclerosis (ALS). The NeuRx RA/4 Diaphragm Pacing System has received Humanitarian ... -
Same-sex sexual behaviour as a dominance display
(2016-04-01)© 2016. Same-sex sexual behaviour (SSB) is widespread across taxa. One adaptive hypothesis to explain the occurrence and maintenance of SSB is that it acts to intensify or diminish aggression by providing males with a ... -
School principals’ views of teaching standards for inclusive education in New Zealand.
(RoutledgeAbingdon, 2014-06-10) -
Scientific Case for Avoiding Dangerous Climate Change to Protect Young People and Nature
(2012-03-23)Global warming due to human-made gases, mainly CO2, is already 0.8{\deg}C and deleterious climate impacts are growing worldwide. More warming is 'in the pipeline' because Earth is out of energy balance, with absorbed solar ... -
Screening and testing for endocrine disruption in fish-biomarkers as "signposts," not "traffic lights," in risk assessment.
(United States, 2006-04)Biomarkers are currently best used as mechanistic "signposts" rather than as "traffic lights" in the environmental risk assessment of endocrine-disrupting chemicals (EDCs). In field studies, biomarkers of exposure [e.g., ... -
Sea-level rise impacts on transport infrastructure: The notorious case of the coastal railway line at Dawlish, England
(Elsevier, 2016-02)Future climate change is likely to increase the frequency of coastal storms and floods, with major consequences for coastal transport infrastructure. This paper assesses the extent to which projected sea-level rise is ... -
Sediment fingerprinting in agricultural catchments: A critical re-examination of source discrimination and data corrections
(2014-01-01)Fine sediment source fingerprinting techniques have been widely applied in agricultural river catchments. Successful source discrimination in agricultural environments depends on the key assumption that land-use source ... -
Seladelpar (MBX-8025), a selective PPAR-δ agonist, in patients with primary biliary cholangitis with an inadequate response to ursodeoxycholic acid: a double-blind, randomised, placebo-controlled, phase 2, proof-of-concept study.
(2017-08-14)BACKGROUND: Many patients with primary biliary cholangitis have an inadequate response to first-line therapy with ursodeoxycholic acid. Seladelpar is a potent, selective agonist for the peroxisome proliferator-activated ... -
Selecting GLP-1 agonists in the management of type 2 diabetes: differential pharmacology and therapeutic benefits of liraglutide and exenatide.
(New Zealand, 2010-09-07)Failure of secretion of the incretin hormone glucagon-like peptide-1 (GLP-1) plays a prominent role in type 2 diabetes, and restoration of GLP-1 action is an important therapeutic objective. Although the short duration ...
