Browsing University of Plymouth Research Outputs by Author "29025ab2-bf5d-4288-abc7-814461ba6101"
Now showing items 1-4 of 4
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Hypoxic regulation of RIOK3 is a major mechanism for cancer cell invasion and metastasis.
(England, 2015-09-03)Hypoxia is a common feature of locally advanced breast cancers that is associated with increased metastasis and poorer survival. Stabilisation of hypoxia-inducible factor-1α (HIF1α) in tumours causes transcriptional changes ... -
Nuclear HER4 mediates acquired resistance to trastuzumab and is associated with poor outcome in HER2 positive breast cancer.
(United States, 2014-08-15)The role of HER4 in breast cancer is controversial and its role in relation to trastuzumab resistance remains unclear. We showed that trastuzumab treatment and its acquired resistance induced HER4 upregulation, cleavage ... -
Nuclear HER4 mediates acquired resistance to trastuzumab and is associated with poor outcome in HER2 positive breast cancer.
(United States, 2014-04-17)The role of HER4 in breast cancer is controversial and its role in relation to trastuzumab resistance remains unclear. We showed that trastuzumab treatment and its acquired resistance induced HER4 upregulation, cleavage ...
