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Prospective, multicentre study of external ventricular drainage-related infections in the UK and Ireland.
(2018-02)
OBJECTIVES: External ventricular drain (EVD) insertion is a common neurosurgical procedure. EVD-related infection (ERI) is a major complication that can lead to morbidity and mortality. In this study, we aimed to establish ...
Current epidemiology of cerebrospinal fluid shunt surgery in the UK and Ireland (2004-2013).
(2019-07)
OBJECTIVES: To determine current epidemiology and clinical characteristics of cerebrospinal fluid (CSF) shunt surgery, including revisions. METHODS: A retrospective, multicentre, registry-based study was conducted based ...
Pathophysiology of chronic subdural haematoma: inflammation, angiogenesis and implications for pharmacotherapy.
(2017-05-30)
Chronic subdural haematoma (CSDH) is an encapsulated collection of blood and fluid on the surface of the brain. Historically considered a result of head trauma, recent evidence suggests there are more complex processes ...
Early Hour, Golden Hour: an Exploration of Slovenian Older People's Meaningful Occupations.
(2019-06)
People are occupational beings and enabling older people to engage in meaningful occupations contributes to their health and well-being. Experiences of engagement and meaning in an occupation may differ in different ...
Dexamethasone for adult patients with a symptomatic chronic subdural haematoma (Dex-CSDH) trial: study protocol for a randomised controlled trial.
(2018-12-04)
BACKGROUND: Chronic subdural haematoma (CSDH) is a common neurosurgical condition, typically treated with surgical drainage of the haematoma. However, surgery is associated with mortality and morbidity, including up to 20% ...
Outcomes following surgery in subgroups of comatose and very elderly patients with chronic subdural hematoma.
(2019-06)
Increasing age and lower pre-operative Glasgow coma score (GCS) are associated with worse outcome after surgery for chronic subdural haematoma (CSDH). Only few studies have quantified outcomes specific to the very elderly ...
Identification of Optimum Panel of Blood-based Biomarkers for Alzheimer's Disease Diagnosis Using Machine Learning.
(2018-07)
With the increasing number of people living with Alzheimer's disease (AD), there is a need for low-cost and easy to use methods to detect AD early to facilitate access to appropriate care pathways. Neuroimaging biomarkers ...
Changes in the EEG amplitude as a biomarker for early detection of Alzheimer's disease.
(2016-08)
The rapid increase in the number of older people with Alzheimer's disease (AD) and other forms of dementia represents one of the major challenges to the health and social care systems. Early detection of AD makes it possible ...
Tsallis entropy as a biomarker for detection of Alzheimer's disease.
(2015)
Alzheimer's disease (AD) and other forms of dementia are one of the major public health and social challenges of our time because of the large number of people affected. Early diagnosis is important for patients and their ...
Dex-CSDH randomised, placebo-controlled trial of dexamethasone for chronic subdural haematoma: report of the internal pilot phase.
(2019-04-10)
The Dex-CSDH trial is a randomised, double-blind, placebo-controlled trial of dexamethasone for patients with a symptomatic chronic subdural haematoma. The trial commenced with an internal pilot, whose primary objective ...