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dc.contributor.authorWatkins, ER
dc.contributor.authorTaylor, RS
dc.contributor.authorByng, Richard
dc.contributor.authorBaeyens, C
dc.contributor.authorRead, R
dc.contributor.authorPearson, K
dc.contributor.authorWatson, L
dc.date.accessioned2018-04-12T10:50:06Z
dc.date.available2018-04-12T10:50:06Z
dc.date.issued2012-07
dc.identifier.issn0033-2917
dc.identifier.issn1469-8978
dc.identifier.urihttp://hdl.handle.net/10026.1/11265
dc.description.abstract

<jats:sec id="S0033291711002480_sec_a001"><jats:title>Background</jats:title><jats:p>The development of widely accessible, effective psychological interventions for depression is a priority. This randomized trial provides the first controlled data on an innovative cognitive bias modification (CBM) training guided self-help intervention for depression.</jats:p></jats:sec><jats:sec id="S0033291711002480_sec_a002"><jats:title>Method</jats:title><jats:p>One hundred and twenty-one consecutively recruited participants meeting criteria for current major depression were randomly allocated to treatment as usual (TAU) or to TAU plus concreteness training (CNT) guided self-help or to TAU plus relaxation training (RT) guided self-help. CNT involved repeated practice at mental exercises designed to switch patients from an unhelpful abstract thinking habit to a helpful concrete thinking habit, thereby targeting depressogenic cognitive processes (rumination, overgeneralization).</jats:p></jats:sec><jats:sec id="S0033291711002480_sec_a003" sec-type="results"><jats:title>Results</jats:title><jats:p>The addition of CNT to TAU significantly improved depressive symptoms at post-treatment [mean difference on the Hamilton Rating Scale for Depression (HAMD) 4.28, 95% confidence interval (CI) 1.29–7.26], 3- and 6-month follow-ups, and for rumination and overgeneralization post-treatment. There was no difference in the reduction of symptoms between CNT and RT (mean difference on the HAMD 1.98, 95% CI −1.14 to 5.11), although CNT significantly reduced rumination and overgeneralization relative to RT post-treatment, suggesting a specific benefit on these cognitive processes.</jats:p></jats:sec><jats:sec id="S0033291711002480_sec_a004" sec-type="conclusion"><jats:title>Conclusions</jats:title><jats:p>This study provides preliminary evidence that CNT guided self-help may be a useful addition to TAU in treating major depression in primary care, although the effect was not significantly different from an existing active treatment (RT) matched for structural and common factors. Because of its relative brevity and distinct format, it may have value as an additional innovative approach to increase the accessibility of treatment choices for depression.</jats:p></jats:sec>

dc.format.extent1359-1371
dc.format.mediumPrint-Electronic
dc.languageen
dc.language.isoeng
dc.publisherCambridge University Press (CUP)
dc.subjectCognitive training
dc.subjectdepression
dc.subjectguided self-help
dc.subjectrandomized controlled trial
dc.subjectrumination
dc.titleGuided self-help concreteness training as an intervention for major depression in primary care: a Phase II randomized controlled trial
dc.typejournal-article
dc.typeClinical Trial, Phase II
dc.typeJournal Article
dc.typeRandomized Controlled Trial
dc.typeResearch Support, Non-U.S. Gov't
plymouth.author-urlhttps://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000304441500002&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=11bb513d99f797142bcfeffcc58ea008
plymouth.issue7
plymouth.volume42
plymouth.publication-statusPublished
plymouth.journalPsychological Medicine
dc.identifier.doi10.1017/s0033291711002480
plymouth.organisational-group/Plymouth
plymouth.organisational-group/Plymouth/Faculty of Health
plymouth.organisational-group/Plymouth/Faculty of Health/Peninsula Medical School
plymouth.organisational-group/Plymouth/REF 2021 Researchers by UoA
plymouth.organisational-group/Plymouth/REF 2021 Researchers by UoA/UoA03 Allied Health Professions, Dentistry, Nursing and Pharmacy
plymouth.organisational-group/Plymouth/Research Groups
plymouth.organisational-group/Plymouth/Research Groups/FoH - Community and Primary Care
plymouth.organisational-group/Plymouth/Research Groups/Institute of Health and Community
plymouth.organisational-group/Plymouth/Research Groups/Institute of Translational and Stratified Medicine (ITSMED)
plymouth.organisational-group/Plymouth/Research Groups/Institute of Translational and Stratified Medicine (ITSMED)/CCT&PS
plymouth.organisational-group/Plymouth/Research Groups/Plymouth Institute of Health and Care Research (PIHR)
plymouth.organisational-group/Plymouth/Users by role
plymouth.organisational-group/Plymouth/Users by role/Academics
dc.publisher.placeEngland
dc.identifier.eissn1469-8978
dc.rights.embargoperiodNot known
rioxxterms.versionofrecord10.1017/s0033291711002480
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.typeJournal Article/Review


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