Molecular cloning of a gene encoding a 20S proteasome beta subunit from Plasmodium falciparum.
dc.contributor.author | Li, GD | en |
dc.contributor.author | Li, JL | en |
dc.contributor.author | Mugthin, M | en |
dc.contributor.author | Ward, SA | en |
dc.date.accessioned | 2017-11-27T19:17:03Z | |
dc.date.available | 2017-11-27T19:17:03Z | |
dc.date.issued | 2000-05 | en |
dc.identifier.issn | 0020-7519 | en |
dc.identifier.uri | http://hdl.handle.net/10026.1/10332 | |
dc.description.abstract |
A novel gene was cloned from Plasmodium falciparum. Database searches indicated this gene to be a member of the 20S proteasome beta-subunit family. Comparison of the gene's genomic DNA sequence with cDNA sequence revealed a 156-bp intron 85 bp downstream from the start codon. The nucleotide sequence of the gene contains one open reading frame encoding 265 amino acids with a predicted molecular mass of 30.9 kDa and a pI of 6.2. Northern blot analysis showed the transcript size to be approximately 1.6 kb indicating that some 800 bp of the transcript is non-coding. | en |
dc.format.extent | 729 - 733 | en |
dc.language | eng | en |
dc.language.iso | eng | en |
dc.subject | Adenosine Triphosphatases | en |
dc.subject | Amino Acid Sequence | en |
dc.subject | Animals | en |
dc.subject | Cloning, Molecular | en |
dc.subject | Cysteine Endopeptidases | en |
dc.subject | Humans | en |
dc.subject | Mice | en |
dc.subject | Molecular Sequence Data | en |
dc.subject | Multienzyme Complexes | en |
dc.subject | Plasmodium falciparum | en |
dc.subject | Proteasome Endopeptidase Complex | en |
dc.subject | Protein Conformation | en |
dc.subject | Rats | en |
dc.subject | Sequence Alignment | en |
dc.subject | Xenopus laevis | en |
dc.subject | Zebrafish | en |
dc.title | Molecular cloning of a gene encoding a 20S proteasome beta subunit from Plasmodium falciparum. | en |
dc.type | Journal Article | |
plymouth.author-url | https://www.ncbi.nlm.nih.gov/pubmed/10856507 | en |
plymouth.issue | 6 | en |
plymouth.volume | 30 | en |
plymouth.publication-status | Published | en |
plymouth.journal | Int J Parasitol | en |
dc.identifier.doi | 10.1016/s0020-7519(00)00046-1 | en |
plymouth.organisational-group | /Plymouth | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA/UoA01 Clinical Medicine | |
plymouth.organisational-group | /Plymouth/REF 2021 Researchers by UoA/UoA01 Clinical Medicine/UoA01 Clinical Medicine | |
dc.publisher.place | England | en |
dc.rights.embargoperiod | Not known | en |
rioxxterms.versionofrecord | 10.1016/s0020-7519(00)00046-1 | en |
rioxxterms.licenseref.uri | http://www.rioxx.net/licenses/all-rights-reserved | en |
rioxxterms.type | Journal Article/Review | en |