Now showing items 1-2 of 2
Up-regulation of the Notch ligand Delta-like 4 inhibits VEGF-induced endothelial cell function
(American Society of Hematology, 2006-02-01)
<jats:title>Abstract</jats:title><jats:p>Delta-like 4 (Dll4), a membrane-bound ligand for Notch1 and Notch4, is selectively expressed in the developing endothelium and in some tumor endothelium, and it is induced by vascular ...
Up-regulation of endothelial delta-like 4 expression correlates with vessel maturation in bladder cancer.
PURPOSE: Angiogenesis and vascular endothelial growth factor (VEGF) expression are associated with a poor outcome in bladder cancer. To understand more about the mechanisms, we studied the role of delta-like 4 (DLL4), an ...