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Expression of vascular notch ligand delta-like 4 and inflammatory markers in breast cancer.

Jubb, AM; Soilleux, EJ; Turley, H; Steers, G; Parker, A; Low, I; Blades, J; Li, J-L; Allen, P; Leek, R; Noguera-Troise, I; Gatter, KC; Thurston, G; Harris, AL (2010-04)

Delta-like ligand 4 (Dll4) is a Notch ligand that is predominantly expressed in the endothelium. Evidence from xenografts suggests that inhibiting Dll4 may overcome resistance to antivascular endothelial growth factor ...