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A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesis.

Masiero, M; Simões, FC; Han, HD; Snell, C; Peterkin, T; Bridges, E; Mangala, LS; Wu, SY-Y; Pradeep, S; Li, D; Han, C; Dalton, H; Lopez-Berestein, G; Tuynman, JB; Mortensen, N; Li, J-L; Patient, R; Sood, AK; Banham, AH; Harris, AL; Buffa, FM (2013-08-12)

Limited clinical benefits derived from anti-VEGF therapy have driven the identification of new targets involved in tumor angiogenesis. Here, we report an integrative meta-analysis to define the transcriptional program ...