PEARL is currently undergoing essential maintenance and will be read only (no submissions or deposits). PEARL will be available again to deposit outputs early next week (week commencing 1st March 2021). For any queries contact openresearch@plymouth.ac.uk
Search
Now showing items 1-1 of 1
Complete analysis of the B-cell response to a protein antigen, from in vivo germinal centre formation to 3-D modelling of affinity maturation.
(2003-03)
Somatic hypermutation of immunoglobulin variable region genes occurs within germinal centres (GCs) and is the process responsible for affinity maturation of antibodies during an immune response. Previous studies have focused ...