Browsing 01 University of Plymouth Research Outputs by Subject "Lysosomal-Associated Membrane Protein 2"
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Deficiency of sphingosine-1-phosphate lyase impairs lysosomal metabolism of the amyloid precursor protein. (United States, 2014-06-13)Progressive accumulation of the amyloid β protein in extracellular plaques is a neuropathological hallmark of Alzheimer disease. Amyloid β is generated during sequential cleavage of the amyloid precursor protein (APP) by ...