The Plymouth Student Scientist - Volume 1, No. 1 - 2008https://pearl.plymouth.ac.uk/handle/10026.1/127782024-03-28T08:54:37Z2024-03-28T08:54:37ZNutrient intakes at lunchtime of primary school children in Cornwall: a comparison of school meals and packed lunchesRees, G.Richards, C.Gregory, J.https://pearl.plymouth.ac.uk/handle/10026.1/128032020-10-05T10:42:09Z2008-01-01T00:00:00ZNutrient intakes at lunchtime of primary school children in Cornwall: a comparison of school meals and packed lunches
Rees, G.; Richards, C.; Gregory, J.
2008-01-01T00:00:00ZA Review of Combined Diet and Exercise Weight Loss Interventions in Obese and Overweight AdolescentsLowles, N.https://pearl.plymouth.ac.uk/handle/10026.1/128022020-10-05T10:42:09Z2008-01-01T00:00:00ZA Review of Combined Diet and Exercise Weight Loss Interventions in Obese and Overweight Adolescents
Lowles, N.
2008-01-01T00:00:00ZFactors that Affect Cardiovascular Health: A ReviewBuckingham, S.https://pearl.plymouth.ac.uk/handle/10026.1/128122020-10-05T10:42:09Z2008-01-01T00:00:00ZFactors that Affect Cardiovascular Health: A Review
Buckingham, S.
Cardiovascular disease is a major public health problem in terms of both high
morbidity and mortality rates and large economic costs. Cardiovascular health and risk of
disease are determined by a wide range of genetic and environmental factors. This review
focuses on the extent to which heredity, physical activity, diet, and psychological factors
(including stress) are known to contribute to cardiovascular health or disease. A
predisposition for cardiovascular disease can be inherited, but genetic counselling allows the
identification of those who are most at risk and an individualised plan to include appropriate
lifestyle changes can then be formulated. It is well established that increasing amounts of
physical activity can enhance cardiovascular health and reduce the risk of disease, but
knowledge of specific aspects of exercise (such as optimal intensity and mode) is limited.
Dietary interventions show that reductions in low-density lipoproteins (LDLs), and increases
in high-density lipoproteins (HDLs) and certain antioxidants and vitamins may reduce
cardiovascular disease risk factors. The long-term effects of dietary salt are more
controversial. Psychological factors are contributory, rather than major, determinants of
cardiovascular health, but there is evidence that lack of social support, stress and other
negative states can increase the risk of disease.
2008-01-01T00:00:00ZThe Effect of Nucleotide-binding Oligomerization Domain (NOD) Proteins on the Secretion of Cytokines from MacrophagesAggett, J.https://pearl.plymouth.ac.uk/handle/10026.1/128112020-10-05T10:42:09Z2008-01-01T00:00:00ZThe Effect of Nucleotide-binding Oligomerization Domain (NOD) Proteins on the Secretion of Cytokines from Macrophages
Aggett, J.
The study of Nucleotide-Binding Oligomerization Domain (NOD) Proteins is a very
new area of immunology, with the gene for NOD2 having only been mapped in 2001
(Ogura et al 2001). It holds particular significance for those researching autoimmune
disorders such as Blau syndrome and Crohns Disease (CD), as it has been found
that a mutation in the NOD2 gene is present in a substantial proportion of CD
sufferers, and having the mutation increases a person‟s susceptibility to developing
the disease later in life (Economou et al 2004). This review will look at the current
research surrounding the NOD proteins and what products they form, and how this
can be used to further our knowledge of CD and how it can be managed. It will be
specifically looking into the effects that NOD proteins in macrophages have on the
secretion of various pro- and anti-inflammatory cytokines and how these can be
augmented by the interaction of NOD protein signalling pathways with those of other
molecules in the cell.
2008-01-01T00:00:00Z