Browsing by Subject "autophagy"

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Mycobacterium tuberculosis Infection and Innate Responses in a New Model of Lung Alveolar Macrophages.

Woo, M; Wood, C; Kwon, D; Park, K-HP; Fejer, G; Delorme, V (Switzerland, 2018)

Lung alveolar macrophages (AMs) are in the first line of immune defense against respiratory pathogens and play key roles in the pathogenesis of Mycobacterium tuberculosis (Mtb) in humans. Nevertheless, AMs are available ...
The neurotoxic effects of Manganese and the novel protective role of Drp1 in the autophagy pathway

Sportelli, Carolina (University of Plymouth, 2020)

The precise pathological mechanism of Manganese (Mn) is not yet known however prior evidence suggests a prominent role of mitochondrial dysfunction. Relevant to Parkinson’s disease, Mn is known to bind to α-synuclein and ...