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Now showing items 4236-4255 of 6237
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P-GLYCOPROTEIN-ASSOCIATED ANTHRACYCLINE RESISTANCE IN B-CLL: P0TENTIAL FOR CYTOKINE MODULATION
(University of Plymouth, 2001)The phenomenon of multidrug resistance (MDR) in cancer cells is generally associated with P-glycoprotein (P-gp) expression and presents an obstacle to successful chemotherapy. Attempts to overcome P-gp-associated MDR using ... -
Pain solution in the emergency setting (pasties); an open-label randomised trial of patient-controlled analgesia (pca) versus routine care in patients attending the emergency department with traumatic injuries.
(EnglandEnglandEnglandEnglandEnglandEnglandEnglandEnglandEngland, 2014-09)Pain is the commonest reason that patients present to an Emergency Department (ED), but is often not treated effectively. Patient controlled analgesia (PCA) is used in other hospital settings but there is little evidence ... -
PAin SoluTions In the Emergency Setting (PASTIES)--patient controlled analgesia versus routine care in emergency department patients with non-traumatic abdominal pain: randomised trial.
(EnglandEnglandEnglandEnglandEnglandEnglandEnglandEnglandEnglandEngland, 2015-06-21)OBJECTIVE: To determine whether patient controlled analgesia (PCA) is better than routine care in providing effective analgesia for patients presenting to emergency departments with moderate to severe non-traumatic abdominal ... -
PAin SoluTions In the Emergency Setting (PASTIES)--patient controlled analgesia versus routine care in emergency department patients with pain from traumatic injuries: randomised trial.
(EnglandEnglandEnglandEnglandEnglandEnglandEnglandEnglandEnglandEngland, 2015-06-21)OBJECTIVE: To determine whether patient controlled analgesia (PCA) is better than routine care in patients presenting to emergency departments with moderate to severe pain from traumatic injuries. DESIGN: Pragmatic, ... -
PAin SoluTions In the Emergency Setting (PASTIES); a protocol for two open-label randomised trials of patient-controlled analgesia (PCA) versus routine care in the emergency department.
(EnglandEnglandEnglandEnglandEnglandEnglandEnglandEnglandEnglandEnglandEngland, 2013)INTRODUCTION: Pain is the commonest reason that patients present to an emergency department (ED), but it is often not treated effectively. Patient controlled analgesia (PCA) is used in other hospital settings but there ... -
PAINTING SILENCE
(University of Plymouth, 2002)This research examines the history and theory o f silent' painting to discover why particular paintings were called silent, what the term was meant to signify, and how the quality of silence was discernible in the paintings ... -
Pair production from residues of complex worldline instantons
We study nonperturbative pair production in electric fields with lightlike inhomogeneities, using complex worldline instantons. We show that the instanton contribution to the pair production probability is a complex contour ... -
The Palaeo-ecology and Biostratigraphy of the foraminifera from the Oxfordian of north Dorset
(University of Plymouth, 1997)The Oxfordian rocks of north Dorset are poorly exposed at outcrop. A drilling operation was devised and implemented and the complete sequence of strata from the Weymouth Member of the Oxford Clay Formation through to the ... -
A Palaeoecological approach to understanding the impact of coastal changes in Late Holocene societies using the Isles of Scilly as a case study
(University of Plymouth, 2013)The overall aim of this thesis was to explore the impact of environmental changes (relative sea level increase and climate) on coastal communities and to investigate how these environmental factors controlled subsistence ... -
Palaeoecology of the late Permian mass extinction and subsequent recovery
(Plymouth University, 2015)Climate warming during the latest Permian is associated with the most severe mass extinction event of the Phanerozoic, and the expansion of hypoxic and anoxic conditions into shallow shelf settings. Our understanding of ... -
PALAEOECOLOGY, PALAEOENVIRONMENTAL ANALYSIS AND THEIR APPLICATION TO SEQUENCE STRATIGRAPHY: LOWER CRETACEOUS, LUSITANIAN BASIN, PORTUGAL
(University of Plymouth, 2001)Palaeoecological data can provide key information on depositional environments. This may be critical to the interpretation of marine sedimentary cycles and the recognition of ancient cycles and sequences. Although many ... -
Palaeolimnological evidence for an east-west climate see-saw in the Mediterranean since AD 900
(2012-03-01)During the period of instrumental records, the North Atlantic Oscillation (NAO) has strongly influenced inter-annual precipitation variations in the western Mediterranean, while some eastern parts of the basin have shown ... -
Palaeolimnological study of the history of Loe Pool. Helston, and its catchment
(University of Plymouth, 1987) -
A PALAEOMAGNETIC STUDY OF CRUSTAL ROTATIONS AND THEIR RELATIONSHIP TO THE TECTONICS OF THE ATACAMA AND DOMEYKO FAULT SYSTEMS, NORTHERN CHILE
(University of Plymouth, 1996)A total of 178 sites have been collected for palaeomagnetic analysis from within two strike-slip fault systems in northern Chile (25.4°S - 26.4°S); the Atacama Fault System in the Coastal Cordillera, and the Domeyko Fault ... -
Palmitate-induced impairment of glucose-stimulated insulin secretion precedes mitochondrial dysfunction in mouse pancreatic islets.
(EnglandEnglandEnglandEnglandEnglandEnglandEnglandEnglandEngland, 2016-02-15)It has been well established that excessive levels of glucose and palmitate lower glucose-stimulated insulin secretion (GSIS) by pancreatic β-cells. This β-cell 'glucolipotoxicity' is possibly mediated by mitochondrial ... -
Palynological investigations of Cenomanian chalks and marls from England
(University of Plymouth, 1992)The palynological analysis of chalk and marl samples from Cenomanian sections sampled at high resolution has yielded largely diverse and abundant, well-preserved microplankton assemblages. Four sections have been investigated, ... -
Paradigms for the design of multimedia learning environments in engineering
(University of Plymouth, 1996)The starting point for this research was the belief that interactive multimedia learning environments represent a significant evolution in computer based learning and therefore their design requires a re-examination of ...
