ORCID

Abstract

This reflective commentary provides a personal viewpoint of developments, over the last 3 decades, in the relatively new, multidisciplinary field of ‘eco-genotoxicology,’ also called ‘genetic ecotoxicology’. It aims to outline the scope of the subject area in relation to the historical development of the discipline, critically categorising accomplishments made, taking into account the available information. It also recognises limitations of the existing information and difficulties encountered in this challenging field. Where appropriate, the article makes comparisons to the advances made in human genetic toxicology and radiation biology. The article critically covers the applications of prevailing and emerging tools being used in the field, such as omics, in vitro methodologies, modelling approaches, and artificial intelligence (AI). It also identifies potential areas of development and attempts to credit some of the important personal contributions made in this exciting and challenging subject in relation to human and environmental health.

Publication Date

2025-04-09

Publication Title

Mutation Research - Reviews in Mutation Research

Volume

795

ISSN

1383-5742

Keywords

Artificial Intelligence (AI), Biomarkers, Eco-genotoxicology, In vitro toxicology, Modelling Approaches, Omics, Radioecology

First Page

1

Last Page

15

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