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dc.contributor.authorTulloh, RMR
dc.contributor.authorGarratt, V
dc.contributor.authorTagney, J
dc.contributor.authorTurner-Cobb, J
dc.contributor.authorMarques, E
dc.contributor.authorGreenwood, R
dc.contributor.authorHoward, L
dc.contributor.authorGin-Sing, W
dc.contributor.authorBarton, A
dc.contributor.authorEwings, P
dc.contributor.authorCraggs, P
dc.contributor.authorHollingworth, W
dc.date.accessioned2024-04-24T09:37:00Z
dc.date.available2024-04-24T09:37:00Z
dc.date.issued2018-05-21
dc.identifier.issn2055-5784
dc.identifier.issn2055-5784
dc.identifier.other78
dc.identifier.urihttps://pearl.plymouth.ac.uk/handle/10026.1/22298
dc.description.abstract

BACKGROUND: Pulmonary arterial hypertension (PAH) is an uncommon condition with progressive heart failure and premature death. Treatment costs up to £120,000 per patient per year, and the psychological burden of PAH is substantial. Mindfulness-based stress reduction (MBSR) is an intervention with the potential to reduce this burden, but to date, it has not been applied to people with pulmonary hypertension. We wished to determine whether a trial of MBSR for people with PAH would be feasible. METHODS: A customised gentle MBSR programme of eight sessions was developed for people with physical disability due to PAH, and they were randomised to group-based MBSR or treatment as usual. The completeness of outcome measures including Beck Anxiety Index, Beck Depression Inventory and standard physical assessment at 3 months after randomisation were recorded. Health care utilisation was measured. Attendance at the sessions and the costs involved in delivering the intervention were assessed. Semi-structured interviews were conducted to explore the acceptability of the MBSR intervention and when appropriate the reasons for trial non-participation. RESULTS: Fifty-two patients were recruited, but only 34 were randomised due to patients finding it difficult to travel to sessions. Twenty-two completed all questionnaires and attended all clinics, both routine and additional in order to collect outcomes measures. The MSBR sessions were delivered in Bristol, Cardiff and London, costing, on average, between £2234 (Cardiff) and £4128 (London) per patient to deliver. Attendance at each session averaged between two patients in Bristol and Cardiff and three in London. For those receiving treatment as usual, clinician blinding was achievable. Interviews revealed that people who attended MBSR found it interesting and helpful in managing their symptoms and minimising the psychological component of their disease. CONCLUSIONS: We found that attendance at group MBSR was poor in people with chronic PAH within the context of a trial. Achieving better MBSR intervention attendance or use of an Internet-based programme might maximise the benefit of MBSR.

dc.format.extent78-
dc.format.mediumElectronic-eCollection
dc.languageen
dc.publisherBioMed Central
dc.subjectEconomic evaluation
dc.subjectMindfulness-based stress reduction
dc.subjectPsychology
dc.subjectPulmonary arterial hypertension
dc.titleA pilot randomised controlled trial investigating a mindfulness-based stress reduction (MBSR) intervention in individuals with pulmonary arterial hypertension (PAH): the PATHWAYS study
dc.typejournal-article
dc.typeJournal Article
plymouth.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/29796292
plymouth.issue1
plymouth.volume4
plymouth.publisher-urlhttp://dx.doi.org/10.1186/s40814-018-0270-z
plymouth.publication-statusPublished
plymouth.journalPilot and Feasibility Studies
dc.identifier.doi10.1186/s40814-018-0270-z
plymouth.organisational-group|Plymouth
plymouth.organisational-group|Plymouth|Research Groups
plymouth.organisational-group|Plymouth|Faculty of Health
plymouth.organisational-group|Plymouth|Research Groups|Institute of Health and Community
plymouth.organisational-group|Plymouth|Research Groups|Institute of Translational and Stratified Medicine (ITSMED)
plymouth.organisational-group|Plymouth|Research Groups|Institute of Translational and Stratified Medicine (ITSMED)|CCT&PS
plymouth.organisational-group|Plymouth|Users by role
plymouth.organisational-group|Plymouth|Faculty of Health|Peninsula Medical School
plymouth.organisational-group|Plymouth|Faculty of Health|Peninsula Medical School|PMS - Manual
plymouth.organisational-group|Plymouth|Users by role|Former Academic staff
dc.publisher.placeEngland
dcterms.dateAccepted2018-04-11
dc.date.updated2024-04-24T09:36:57Z
dc.identifier.eissn2055-5784
rioxxterms.versionofrecord10.1186/s40814-018-0270-z


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